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The New GentleWave® System

There are challenges in root canal treatment that are beyond the reach of the most skilled hands. Uninstrumented spaces. Undetected canals. Multi-species biofilm. Patient pain and anxiety.

Adding GentleWave® augments your ability to meet these challenges with ease.

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GentleWave G4 System

Beyond irrigation. Beyond clean.

See how GentleWave® excels at debridement and disinfection.

G4 Interior Video play

Designed to go the Distance

The GentleWave® System takes you beyond canal complexity that can hinder thorough disinfection and debridement.

It starts inside the console, where the irrigant is thoroughly degassed, precisely diluted and continuously refreshed. Next, it enters the sealed, closed loop delivery system, where the system’s physics-accelerated chemistry becomes truly remarkable.*

Controlled Cavitation

As the irrigant reaches the head of the procedure instrument, it passes through a narrow orifice, creating a continuous cavitation cloud of tiny, imploding vapor bubbles.

Multisonic Activation

These implosions create a constant barrage of shockwaves able to physically and chemically disrupt and dissolve pulp, biofilm, and other organic and inorganic debris. This is the multsonic energy of the GentleWave® system.

Thorough Disinfection

The ultrasonic energy vibrates throughout the root system unhindered, including fine anatomy, and accelerates the chemistry of the irrigant. This dramatically speeds up debridement and disinfection.

Apical Protection

Simultaneously, as the irrigant stream passes over the root canal system opening, vortical flow is created. True to physics, this produces a negative pressure environment which guards against apical extrusion.

Refreshed Irrigation

The vortical flow creates tornado-like spirals which descend then rise, lifting debris up and out of the canal, and allowing irrigant to be continuously refreshed.

*Data on file. Sonendo, Inc.

†Haapasalo M, Wang Z, Shen Y, Curtis A, Patel P, Khakpour M. Tissue dissolution by a novel multisonic ultracleaning system and sodium hypochlorite. J Endod. 2014;40:1178–1181.

Proof Positive

A body of clinical research. And 1,000,000 real world procedures and counting.

Clean Beyond Compare

Predictably removes up to 99.9% of biofilm1

Cleans up to 98.1% of organic tissue in mesial canals2

Effectively disinfects and debrides uninstrumented, undetected and intricate anatomies2,3

Apical, Efficacy, Achieved

4X - 8.5X greater penetration into dentinal tubules vs. ulstrasonic systems4

Superior debridement in the apical third of mesial conals2

Unsurpassed cleaning in apical-thirds5,6

Safety by Design

Negative apical pressure across apical sizes and canal types7,8

Not associated with extrusion in curved and straight distal canals9

Designed for Procedural Ease

Designed for Procedural Ease

An instrument custom-designed for your high-precision needs meets an interface that simplifies your procedures.

CleanFlow Procedure Instrument

Streamlined Setup

The refined design eliminates the need for sealing caps and depth gauges

Straightforward Access

A sleek, low-profile instrument head permits easy access and a better approach angle for posterior teeth

Procedure Visibility

The FlowView™ window and audible SoundCue™ assist in confirming the sealed environment

Interface & Software

Intuitive Interface

Guides you through the procedure step by step

Irrigant Flexibility

Choose from protocols with varying fluid concentrations and times, including a 0.5% NaOCI option

Workflow Efficiency

Integrated TDO software organizes and tracks your procedure data

Remote Diagnostic Evaluations

Wireless connectivity enables remote procedure review and automatic upgrades

Designed for the Patient Experience

Every case is another opportunity to lessen the stress around root canal treatment—both during and afterwards—and help drive referrals.

Positive Treatment Outcomes

Little to no post-treatment pain

96.6% of patients report mild to no pain within 48 hours10

Rapid rates of healing

97.7% 12-month healing rate11

Positive Treatment Experience

Single-handed cleaning and disinfection

The procedure instrument enables one-handed procedures for greater comfort

Minimal noise

The system’s multisonic frequencies are audible as white noise

1. Zhang D, Shen Y, de la Fuente-Núñez C, Haapasalo M. In vitro evaluation by quantitative real-time PCR and culturing of the effectiveness of disinfection of multispecies biofilms in root canals by two irrigation systems. Clin Oral Investig. 2019 Feb;23(2):913-920. doi: 10.1007/s00784-018-2515-x. Epub 2018 Jun 15. PMID: 29948281.

2. Molina B, Glickman G, Vandrangi P, Khakpour M. Evaluation of Root Canal Debridement of Human Molars Using the GentleWave System. J Endod. 2015 Oct;41(10):1701-5. doi: 10.1016/j.joen.2015.06.018. Epub 2015 Aug 12. PMID: 26275599.

3. Wang Z, Shen Y, Haapasalo M. Root Canal Wall Dentin Structure in Uninstrumented but Cleaned Human Premolars: A Scanning Electron Microscopic Study. J Endod. 2018 May;44(5):842-848. doi: 10.1016/j.joen.2018.01.014. Epub 2018 Mar 15. PMID: 29550004.

4. Vandrangi P (2016) Evaluating Penetration Depth of Treatment Fluids into Dentinal Tubules Using the GentleWave® System. Dentistry 6: 366. doi:10.4172/2161-1122.1000366

5. Ma J, Shen Y, Yang Y, Gao Y, Wan P, Gan Y, Patel P, Curtis A, Khakpour M, Haapasalo M. In vitro study of calcium hydroxide removal from mandibular molar root canals. J Endod. 2015 Apr;41(4):553-8. doi: 10.1016/j.joen.2014.11.023. Epub 2015 Jan 14. PMID: 25596727.

6. Jaramillo DE, & Arriola AR. Histological Evaluation of Multisonic Technology for Debridement of Vital and Necrotic Pulp Tissues from Human Molar Teeth. An Observational Study. Appl. Sci. 2021; 11, 11002.

7. Haapasalo M, Shen Y, Wang Z, Park E, Curtis A, Patel P, Vandrangi P. Apical pressure created during irrigation with the GentleWaveTM system compared to conventional syringe irrigation. Clin Oral Investig. 2016 Sep;20(7):1525-34. doi: 10.1007/s00784-015-1632-z. Epub 2015 Oct 26. PMID: 26498770.

8. Chen B, Shen Y, Ma J, & Haapasalo M. Effect of apical size on apical pressure during syringe-needle and multisonic negative pressure irrigation. Odontology. 2021; 109: 625-631.

9. Charara K, Friedman S, Sherman A, Kishen A, Malkhassian G, Khakpour M, Basrani B. Assessment of Apical Extrusion during Root Canal Irrigation with the Novel GentleWave System in a Simulated Apical Environment. J Endod. 2016 Jan;42(1):135-9. doi: 10.1016/j.joen.2015.04.009. Epub 2015 Nov 4. PMID: 26547720.

10. Data on file. Sonendo, Inc.

11. Sigurdsson A, Garland RW, Le KT & Rassoulian SA. Healing of Periapical Lesions After Endodontic
Treatment with the GentleWave Procedure: A Prospective Multicenter Clinical Study. Journal of Endodontics. 2018;44(3):510-517.